Dermatopathology

Tricky Residual BCC on deeper

Basal cell carcinoma, infiltrative micronodular type with perineural infiltration. Discontiguous atypical basaloid foci are identified, of which these micronodular foci exhibit clear cut perineural infiltration. The perineural foci involve the margins of resection.

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Slide 1: 60 year old female. This specimen was received as a re-excision for a cheek basal cell carcinoma that closely approached the surgical margin.

Slide 2: Is there any evidence of residual BCC?

Slide 3: A hair follicle?

Slide 4: Notice the two tapered nuclei in the center of the "hair follicle".

Slide 5: Deeper sections were requested.

Slide 6: Residual BCC entrapping a nerve. The spindled wavy nuclei can be appreciated on this section.