Dermatopathology

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Thrombophlebitis

The findings are diagnostic of a superficial thrombophlebitis. Thrombophlebitis manifesting this particular morphology being of striking thrombotic vascular occlusion can be indicative of an underlying procoagulant state including the procoagulant state that would be reflective of a syndrome such as Behcet's disease, antiphospholipid antibody syndrome, acquired protein S deficiency or Factor-V Leiden. In addition certain tumors can evoke a prothrombotic tendency due to the elaboration of certain cytokine such as thromboplastin perhaps best exemplified by pancreatic cancer.

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