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Dermatopathology

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Perniosis

TPerniosis is characterized by the development of skin lesions in response to cold exposure. Lesions are erythematous, most commonly occur on the fingers and toes and range in appearance from macules to nodules. The pathogenesis likely involves cold-induced vasoconstriction with subsequent hypoxia and inflammation. When perniosis occurs in individuals with hematologic disorders, autoimmune disease or malignancy it is referred to as secondary perniosis. When skin lesions arise in patients with lupus erythematosus, they are referred to as lesions of chilblain lupus erythematosus.

The diagnosis in this case is perniosis with features of the so called second variant as seen within the spectrum of lupus erythematous (Chilblains Lupus Erythematosus).

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