Perineuriomas are uncommon benign peripheral nerve sheath tumors that can arise dermally, subcutaneously or in deep soft tissue. Soft tissue perineuriomas most commonly arise at acral sites however, extra-acral tumors have been reported (trunk, head and neck, retroperitoneum, paratesticular). They are benign tumors that are well circumscribed and characterized by a proliferation of spindle cells that assume a whorled or fascicular growth pattern. The stroma can vary from myxoid to collagenous and sclerotic.
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