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Dermatopathology

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Home > Clinicians > Diagnosis Gallery > Acantholytic Acanthoma

Acantholytic Acanthoma

This is a benign lesion which usually presents in older patients as a solitary painless papule of the trunk. Histologically, the lesions are characterized by an acanthotic epidermis along with acantholysis that most frequently affects the suprabasilar portion of the stratum spinosum.

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Slide 1: 70 year-old woman with a presternal lesion. There is acanthosis with supervening acantholytic dyskeratosis and overlying parakeratosis.
Slide 2: There is acanthosis with supervening acantholytic dyskeratosis and overlying parakeratosis.
Slide 3: The findings are consistent with an acantholytic acanthoma.
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